We report on the treatment with micafungin of a pacemaker-associated endocarditis due to Candida albicans. Antifungal therapy was able to reduce vegetation size from 5 to 1 cm making possible the transvenous removal of the device without a high risk of pulmonary embolism. Noteworthy, a high micafungin concentration was documented into the lead vegetation (10 microg/g of vegetation tissue) and this may have contributed to the striking size reduction of vegetation.

Micafungin for Candida Albicans Pacemaker-Associated Endocarditis: A Case Report and Review of the Literature

Tascini C;DI PAOLO, ANTONELLO;Di Cori A;Menichetti F.
2013-01-01

Abstract

We report on the treatment with micafungin of a pacemaker-associated endocarditis due to Candida albicans. Antifungal therapy was able to reduce vegetation size from 5 to 1 cm making possible the transvenous removal of the device without a high risk of pulmonary embolism. Noteworthy, a high micafungin concentration was documented into the lead vegetation (10 microg/g of vegetation tissue) and this may have contributed to the striking size reduction of vegetation.
2013
Tascini, C; Bongiorni, Mg; Tagliaferri, E; DI PAOLO, Antonello; Flammini, S; Soldati, E; Leonildi, A; Di Cori, A; Menichetti, F.
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11568/159544
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