We report on the treatment with micafungin of a pacemaker-associated endocarditis due to Candida albicans. Antifungal therapy was able to reduce vegetation size from 5 to 1 cm making possible the transvenous removal of the device without a high risk of pulmonary embolism. Noteworthy, a high micafungin concentration was documented into the lead vegetation (10 microg/g of vegetation tissue) and this may have contributed to the striking size reduction of vegetation.
|Autori:||Tascini C; Bongiorni MG; Tagliaferri E; Di Paolo A; Flammini S; Soldati E; Leonildi A; Di Cori A; Menichetti F|
|Titolo:||Micafungin for Candida Albicans Pacemaker-Associated Endocarditis: A Case Report and Review of the Literature|
|Anno del prodotto:||2013|
|Digital Object Identifier (DOI):||10.1007/s11046-012-9591-2|
|Appare nelle tipologie:||1.1 Articolo in rivista|