We report on the treatment with micafungin of a pacemaker-associated endocarditis due to Candida albicans. Antifungal therapy was able to reduce vegetation size from 5 to 1 cm making possible the transvenous removal of the device without a high risk of pulmonary embolism. Noteworthy, a high micafungin concentration was documented into the lead vegetation (10 microg/g of vegetation tissue) and this may have contributed to the striking size reduction of vegetation.

Micafungin for Candida Albicans Pacemaker-Associated Endocarditis: A Case Report and Review of the Literature

Tascini C;DI PAOLO, ANTONELLO;
2013-01-01

Abstract

We report on the treatment with micafungin of a pacemaker-associated endocarditis due to Candida albicans. Antifungal therapy was able to reduce vegetation size from 5 to 1 cm making possible the transvenous removal of the device without a high risk of pulmonary embolism. Noteworthy, a high micafungin concentration was documented into the lead vegetation (10 microg/g of vegetation tissue) and this may have contributed to the striking size reduction of vegetation.
2013
Tascini, C; Bongiorni, Mg; Tagliaferri, E; DI PAOLO, Antonello; Flammini, S; Soldati, E; Leonildi, A; Di Cori, A; Menichetti, F.
File in questo prodotto:
File Dimensione Formato  
159544.PDF

solo utenti autorizzati

Tipologia: Versione finale editoriale
Licenza: NON PUBBLICO - Accesso privato/ristretto
Dimensione 5.12 MB
Formato Adobe PDF
5.12 MB Adobe PDF   Visualizza/Apri   Richiedi una copia

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11568/159544
 Attenzione

Attenzione! I dati visualizzati non sono stati sottoposti a validazione da parte dell'ateneo

Citazioni
  • ???jsp.display-item.citation.pmc??? 5
  • Scopus 14
  • ???jsp.display-item.citation.isi??? 15
social impact