Neonatal Isoerythrolysis (NI) is due to antierythrocyte isoantibodies produced by the mare following a stimulation during one or more pregnancies and concentrated in the colostrum. For this reason, the foal shows a healthy condition at birth and develops the disease following the intake of colostrum. In this paper are reported and analysed the results of investigations during 15 years about the occurrence of NI in Italy. The true diagnosis of this neonatal disease is possible only by means of appropriate immuno-hematological exams which also allow a convenient disease prevention. The blood group analysis on 2,771 mares, mostly collected from purebred Arabians, has allowed to identify animals at risk for Aa and Qa factors. Furthermore, an investigation on the occurrence and titre of antierythrocyte isoantibodies in blood serum of 78 mares has been carried out by means of haemoagglutination and haemolysis techniques. From this further survey, an immunological reaction against the Aa antigen was evidenced in three mares, while in one mare for Da antigen and in another one for De antigen.
Studio retrospettivo sull'incidenza dell'isoeritrolisi neonatale nel puledro
GUGLIUCCI, BIANCAURORA;LUBAS, GEORGE;GAVAZZA, ALESSANDRA;
1999-01-01
Abstract
Neonatal Isoerythrolysis (NI) is due to antierythrocyte isoantibodies produced by the mare following a stimulation during one or more pregnancies and concentrated in the colostrum. For this reason, the foal shows a healthy condition at birth and develops the disease following the intake of colostrum. In this paper are reported and analysed the results of investigations during 15 years about the occurrence of NI in Italy. The true diagnosis of this neonatal disease is possible only by means of appropriate immuno-hematological exams which also allow a convenient disease prevention. The blood group analysis on 2,771 mares, mostly collected from purebred Arabians, has allowed to identify animals at risk for Aa and Qa factors. Furthermore, an investigation on the occurrence and titre of antierythrocyte isoantibodies in blood serum of 78 mares has been carried out by means of haemoagglutination and haemolysis techniques. From this further survey, an immunological reaction against the Aa antigen was evidenced in three mares, while in one mare for Da antigen and in another one for De antigen.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
