Stretch-activated cation channels were identified in the soma membrane of leech central neurons. These channels were almost silent under normal experimental conditions and were distinctly activated by application of negative pressure to the patch pipette. The channels exhibited a preferential selectivity for K+ and a slope conductance of about 200 pS, in symmetrical K+ solution. In cell-attached patches these cation channels were activated by cell swelling.
|Autori:||PELLEGRINO M.; PELLEGRINI M.; SIMONI A.; GARGINI C.|
|Titolo:||Stretch-activated cation channels with large unitary conductance in leech central neurons|
|Anno del prodotto:||1990|
|Digital Object Identifier (DOI):||10.1016/000689939090883d|
|Appare nelle tipologie:||1.1 Articolo in rivista|