Autoantibodies reacting with bromelain-treated autologous mouse red blood cells (Br-MRBC) are spontaneously produced by normal mice. In order to understand the biological significance of these autoantibodies, anti-Br-MRBC monoclonal autoantibodies have been prepared and studied for reactivity with a panel of frozen tissue sections from organs of normal mice by direct immunofluorescence. It has been found that the anti-Br-MRBC monoclonal autoantibodies are polyspecific, since they react with cells in multiple organs.

MULTIPLE ORGAN-REACTIVITY OF MONOCLONAL AUTOANTIBODIES TO MOUSE ERYTHROCYTES

GARZELLI, CARLO;BASOLO, FULVIO;
1987-01-01

Abstract

Autoantibodies reacting with bromelain-treated autologous mouse red blood cells (Br-MRBC) are spontaneously produced by normal mice. In order to understand the biological significance of these autoantibodies, anti-Br-MRBC monoclonal autoantibodies have been prepared and studied for reactivity with a panel of frozen tissue sections from organs of normal mice by direct immunofluorescence. It has been found that the anti-Br-MRBC monoclonal autoantibodies are polyspecific, since they react with cells in multiple organs.
1987
Garzelli, Carlo; Basolo, Fulvio; Puglisi, C; Pacciardi, A.
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11568/173281
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