Event-related potentials (ERPs), elicited by an auditory odd-ball paradigm (P300) were recorded in 37 epileptic patients (Ep; 10 with primary generalized and 27 with partial seizures) and in 30 age-matched controls. Ep showed significantly prolonged N2 and P3 latencies, and in a less degree N1, compared with controls. By considering single cases, 40% with generalized epilepsy and 66% with partial seizures had P300 abnormalities. A positive correlation between the seizure frequency, polytherapy and P300 changes was noted. Our findings suggest the use of P300 in evaluation of Ep
Modificazioni della componente P300 in pazienti con epilessia
SARTUCCI, FERDINANDO;BONANNI, ENRICA;Bonfiglio L;
1994-01-01
Abstract
Event-related potentials (ERPs), elicited by an auditory odd-ball paradigm (P300) were recorded in 37 epileptic patients (Ep; 10 with primary generalized and 27 with partial seizures) and in 30 age-matched controls. Ep showed significantly prolonged N2 and P3 latencies, and in a less degree N1, compared with controls. By considering single cases, 40% with generalized epilepsy and 66% with partial seizures had P300 abnormalities. A positive correlation between the seizure frequency, polytherapy and P300 changes was noted. Our findings suggest the use of P300 in evaluation of EpFile in questo prodotto:
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