1. Introduction 2 2. Pyrrole Derivatives with Two Aryl Groups on Adjacent Positions 2 2.1. Biologically active natural and unnatural pyrrole derivatives with two aryl groups on adjacent positions 2 2.2 Synthesis of pyrrole derivatives with two aryl groups on adjacent positions 5 2.2.1 Synthesis of 1,2-diaryl-1H-pyrroles 5 2.2.2 Synthesis of 2,3- (4,5-)diaryl-1H-pyrroles 9 2.2.3 Synthesis of 3,4-diaryl-1H-pyrroles 12 2.2.4 Synthesis of 1,2,3- (1,4,5-), 1,2,4-, 1,2,5-, 1,3,4-, 2,3,4- (3,4,5-) and 2,3,5-triaryl-1H-pyrroles, 1,2,3,5- and 2,3,4,5- tetraaryl-1H-pyrroles, 1,2,3,4,5-pentaaryl-1H-pyrroles, and 2,3,3.triaryl-2H-pyrroles 16 3. Synthesis of 1-, 2- and 3-Pyrrolines with Two Aryl groups on Adjacent Positions 20 4. Synthesis of 3-Pyrrolin-2-ones and 2,3-Dihydro-1H-pyrrole-2,3-diones with Two Aryl Groups on Adjacent Positions 21 5. Synthesis of Pyrrolidines, 2-Pyrrolidinones, 3-Hydroxy-3-pyrrolin-2-ones and Pyrrolidine-2,4-diones with Two Aryl Groups on Adjacent Positions 25 6. 2,3-Diarylmaleimides (3,4-Diaryl-3-pyrroline-2,5-diones) and 2,3-Diarylsuccinimides (3,4-Diarylpyrrolidine-2,5-diones) 27 6.1. Biologically active natural and unnatural 2,3-diarylmaleimides 27 6.2 Synthesis of symmetrical and unsymmetrical 2,3-diarylmaleimides and 2,3-diarylsuccinimides 29 7. Conclusions and Perspectives 32 Acknowledgements 33 References and notes 33 I

Synthesis and biological activity of pyrrole, pyrroline and pyrrolidine derivatives with two aryl groups on adjacent positions

BELLINA, FABIO;ROSSI, RENZO
2006

Abstract

1. Introduction 2 2. Pyrrole Derivatives with Two Aryl Groups on Adjacent Positions 2 2.1. Biologically active natural and unnatural pyrrole derivatives with two aryl groups on adjacent positions 2 2.2 Synthesis of pyrrole derivatives with two aryl groups on adjacent positions 5 2.2.1 Synthesis of 1,2-diaryl-1H-pyrroles 5 2.2.2 Synthesis of 2,3- (4,5-)diaryl-1H-pyrroles 9 2.2.3 Synthesis of 3,4-diaryl-1H-pyrroles 12 2.2.4 Synthesis of 1,2,3- (1,4,5-), 1,2,4-, 1,2,5-, 1,3,4-, 2,3,4- (3,4,5-) and 2,3,5-triaryl-1H-pyrroles, 1,2,3,5- and 2,3,4,5- tetraaryl-1H-pyrroles, 1,2,3,4,5-pentaaryl-1H-pyrroles, and 2,3,3.triaryl-2H-pyrroles 16 3. Synthesis of 1-, 2- and 3-Pyrrolines with Two Aryl groups on Adjacent Positions 20 4. Synthesis of 3-Pyrrolin-2-ones and 2,3-Dihydro-1H-pyrrole-2,3-diones with Two Aryl Groups on Adjacent Positions 21 5. Synthesis of Pyrrolidines, 2-Pyrrolidinones, 3-Hydroxy-3-pyrrolin-2-ones and Pyrrolidine-2,4-diones with Two Aryl Groups on Adjacent Positions 25 6. 2,3-Diarylmaleimides (3,4-Diaryl-3-pyrroline-2,5-diones) and 2,3-Diarylsuccinimides (3,4-Diarylpyrrolidine-2,5-diones) 27 6.1. Biologically active natural and unnatural 2,3-diarylmaleimides 27 6.2 Synthesis of symmetrical and unsymmetrical 2,3-diarylmaleimides and 2,3-diarylsuccinimides 29 7. Conclusions and Perspectives 32 Acknowledgements 33 References and notes 33 I
Bellina, Fabio; Rossi, Renzo
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Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/11568/181942
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