Bactericidal activity of human beta-defensin 3 (hBD-3) against Streptococcus mutans and Actinobacillus actinomycetemcomitans was inhibited in a dose-dependent manner by the presence of saliva and/or serum. Increasing the concentration of hBD-3 partially overcame this inhibition. A fast bactericidal effect was observed against both bacterial strains, suggesting a potential therapeutic use for hBD-3 in the local treatment of oral infections.
Susceptibility of Streptococcus mutans and Actinobacillus actinomycetemcomitans to Bactericidal Activity of Human beta-Defensin 3 in Biological Fluids
MAISETTA, GIUSEPPANTONIO;BATONI, GIOVANNA;ESIN, SEMIH;BOTTAI, DARIA;FAVILLI, FLAVIA;FLORIO, WALTER;CAMPA, MARIO
2005-01-01
Abstract
Bactericidal activity of human beta-defensin 3 (hBD-3) against Streptococcus mutans and Actinobacillus actinomycetemcomitans was inhibited in a dose-dependent manner by the presence of saliva and/or serum. Increasing the concentration of hBD-3 partially overcame this inhibition. A fast bactericidal effect was observed against both bacterial strains, suggesting a potential therapeutic use for hBD-3 in the local treatment of oral infections.File in questo prodotto:
Non ci sono file associati a questo prodotto.
I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
