Background. A few studies suggest that different neurotransmitters may play a role in the expression of jealousy. Our study aimed to explore the serotonergic system by means of the specific binding of H-3-paroxetine (H-3-Par) to platelet membranes of healthy subjects with and without excessive jealousy concerns, according to a specific self-administered questionnaire [Questionnaire for affective relationships (QAR)]. Subjects and Methods: The study sample includes 21 subjects concerned by jealousy thoughts and 21 control subjects without jealousy concerns, as shown by their OAR scores. Subjects of the first group were administered a battery of self-report instruments designed to detect the presence of typical, atypical and subthreshold psychopathology. Platelet membranes and 3H-Par binding were carried out according to standardized protocols. Results: Subjects with excessive jealousy concerns had a reduced density of H-3-Par binding as compared with control subjects without jealousy concerns and had one or more psychiatric spectrum conditions. Conclusions: Our findings suggest that excessive jealousy is associated with various forms of psychopathology and may be underlain by alteration of the serotonergic system, as reflected by the lower density of the platelet serotonin transporter. Copyright (C) 2003 S. Karger AG, Basel.
|Autori interni:||ROSSI, ALESSANDRA|
|Autori:||Marazziti D; Rucci P; Di Nasso E; Masala I; Baroni S; Rossi A; Giannaccini G; Mengali F; Lucacchini A|
|Titolo:||Jealousy and subthreshold psychopathology: A serotonergic link|
|Anno del prodotto:||2003|
|Digital Object Identifier (DOI):||10.1159/000068869|
|Appare nelle tipologie:||1.1 Articolo in rivista|