Six triterpenoids having a lupane and oleane skeleton were isolated from the leaves and young branches of Licania heteromorpha Bentham var, heteromorpha and were identified as: betulinic acid 1, alphitolic acid 2, 3 beta -O-trans-p-coumaroyl alphitolic acid 3, 3 beta -O-cis-p-coumaroyl alphitolic acid 4, 3 beta -O-trans-p-coumaroyl maslinic acid 5, 3 beta -O-cis-p-coumaroyl maslinic acid 6. The antimicrobial activity of these compounds was evaluated in vitro on clinically isolated microorganisms employing a microdilution method. Compounds 2, 3, 5, and 6 showed antimicrobial activity on Cram-positive bacteria and yeasts, whereas none of the six triterpenoids were active against Gram-negative organisms.
|Autori:||A. BRACA; I. MORELLI; J. MENDEZ; L. BATTINELLI; L. BRAGHIROLI; G. MAZZANTI|
|Titolo:||Antimicrobial triterpenoids from Licania heteromorpha|
|Anno del prodotto:||2000|
|Digital Object Identifier (DOI):||10.1055/s-2000-9601|
|Appare nelle tipologie:||1.1 Articolo in rivista|