Pseudomonas cepacia lipase (PCL) has been immobilized by coating the enzyme on an epoxysilica HPLC column. The biocatalyst has been successfully used for the preparation of both the enantiomers of 3-acetoxy-2-benzyl- propan-1-ol and of 3-acetoxy-2-methylpropan-1-ol. The immobilized enzyme is active after months of use either in aqueous or in organic media.
Lipase-based HPLC Stationary Phase: Enantioselective Synthesis of 2-Substituted 1,3-Propanediol Monoacetates
PETRI, ANTONELLA;
1999-01-01
Abstract
Pseudomonas cepacia lipase (PCL) has been immobilized by coating the enzyme on an epoxysilica HPLC column. The biocatalyst has been successfully used for the preparation of both the enantiomers of 3-acetoxy-2-benzyl- propan-1-ol and of 3-acetoxy-2-methylpropan-1-ol. The immobilized enzyme is active after months of use either in aqueous or in organic media.File in questo prodotto:
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