Cytotoxic T lymphocytes (CTLs) are important effectors in host immune responses to intracellular pathogens and tumors and have been shown to play a critical role in the control of HIV infection ( [Koup et al., 1994] and [Rowland-Jones et al., 1997]). Efficient and accurate measurement of CTL activity is therefore important for the evaluation of cellular immune responses to viral infections and in assisting the design of immunotherapeutic interventions and vaccines.
|Autori:||Bonci F; Zabogli E; Freer G; Merico A; Bendinelli M; Pistello M|
|Titolo:||A new fluorimetric assay to measure cytotoxic T-lymphocyte activity against feline immunodeficiency virus envelope glycoprotein|
|Anno del prodotto:||2008|
|Digital Object Identifier (DOI):||10.1016/j.vetimm.2008.01.021|
|Appare nelle tipologie:||1.1 Articolo in rivista|