Cytotoxic T lymphocytes (CTLs) are important effectors in host immune responses to intracellular pathogens and tumors and have been shown to play a critical role in the control of HIV infection ( [Koup et al., 1994] and [Rowland-Jones et al., 1997]). Efficient and accurate measurement of CTL activity is therefore important for the evaluation of cellular immune responses to viral infections and in assisting the design of immunotherapeutic interventions and vaccines.
A new fluorimetric assay to measure cytotoxic T-lymphocyte activity against feline immunodeficiency virus envelope glycoprotein
FREER, GIULIAWriting – Original Draft Preparation
;BENDINELLI, MAUROWriting – Original Draft Preparation
;PISTELLO, MAURO
Writing – Review & Editing
2008-01-01
Abstract
Cytotoxic T lymphocytes (CTLs) are important effectors in host immune responses to intracellular pathogens and tumors and have been shown to play a critical role in the control of HIV infection ( [Koup et al., 1994] and [Rowland-Jones et al., 1997]). Efficient and accurate measurement of CTL activity is therefore important for the evaluation of cellular immune responses to viral infections and in assisting the design of immunotherapeutic interventions and vaccines.File in questo prodotto:
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