We evaluated the effects on glucose and lipid metabolism in 57 healthy volunteers randomly assigned to one of three low-dose oral contraceptives: two monophasic (desogestrel + ethinylestradiol, EE, and cyproterone acetate + EE) and one triphasic (gestodene + EE) contraceptives. Glucose and insulin responses during OGTT were slightly affected by the cyproterone pill. The insulin area/glucose area ratio and HbA1c level were unchanged in all women. No preparation affected total and LDL-cholesterol levels. Triglycerides rose in all groups, while HDL-CH did only in women taking the two monophasic pills. The three low-dose pills assessed in this study have negligible effects on glucose and lipid metabolism.
|Autori:||Miccoli R; Orlandi MC; Fruzzetti F; Giampietro O; Melis G; Ricci C; Bertolotto A; Fioretti P; Navalesi R|
|Titolo:||Metabolic effects of three new low-dose pills: a six-month experience.|
|Anno del prodotto:||1989|
|Appare nelle tipologie:||1.1 Articolo in rivista|