A statistical parametric model of returning echoes from myocardium is theorized in order to investigate the relationship between normal myocardium structure and spectral signatures with the use of ultrasonic tissue characterization. It is hypothesized, that in a clinical setting the normal myofiber architecture in the left ventricular wall is structured as a matrix of cylinder scatterers whose orientation and spatial distribution vary according to two different statistical distribution laws: 1) a Gaussian law to approximate parametric angular myofiber variability at each site within the myocardial wall; 2) a gamma distribution law to describe parametric regularity in scatterer interdistance. In the model, the effect of the angle of insonification with respect to the alignment of myofibers on ultrasound backscatter was considered. The slope of the power spectral density (PSD) evaluated within the echocardiographic transducer bandwidth has been used as a ultrasonic tissue characterization parameter. The model has been tested by computer simulation and in vitro measurements on myocardial pig tissue specimens. The concordance between experimental and simulated results confirms that the model accounts for the process underlying the echo formation from normal myocardium. Moreover, it provides a simple method of simulation which can be easily implemented and used for the assessment of pathologic alterations.
|Autori:||Santarelli MF; Landini L|
|Titolo:||A model of ultrasound backscatter for the assessment of myocardial tissue structure and architecture|
|Anno del prodotto:||1996|
|Digital Object Identifier (DOI):||10.1109/10.532124|
|Appare nelle tipologie:||1.1 Articolo in rivista|