A novel regiodivergent kinetic resoln. of a series of allylic epoxides with alkylzinc reagents is described.  Results demonstrate the potential of chiral copper-phosphoramidite catalysts for enantiomer differentiation of allylic epoxides, allowing a chiral catalyst-stereoregulated synthesis of cyclic allylic and homoallylic alcs. with high optical purities.

Catalytic Regiodivergent Kinetic Resolution of Allylic Epoxides: a New Entry to Allylic and Homoallylic Alcohols with High Optical Puriy

PINESCHI, MAURO;CROTTI, PAOLO;DI BUSSOLO, VALERIA;
2004

Abstract

A novel regiodivergent kinetic resoln. of a series of allylic epoxides with alkylzinc reagents is described.  Results demonstrate the potential of chiral copper-phosphoramidite catalysts for enantiomer differentiation of allylic epoxides, allowing a chiral catalyst-stereoregulated synthesis of cyclic allylic and homoallylic alcs. with high optical purities.
Pineschi, Mauro; DEL MORO, F.; Crotti, Paolo; DI BUSSOLO, Valeria; Macchia, F.
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Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/11568/199374
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