Inhaled corticosteroids, long-acting beta2-adrenoceptor agonists, and leukotriene receptor antagonists are widely used for treatment of asthma. Inhaled corticosteroids are recommended as first-line therapy, whereas long-acting beta2-adrenoceptor agonists and leukotriene receptor antagonists are indicated as add-on therapy in patients not adequately controlled with corticosteroids alone. A number of studies have investigated the efficacy of combinations of these drugs in asthma, but several issues concerning the safety of these treatments are highly debated. This review provides a critical appraisal of the tolerability profiles of long-acting beta2-agonists and leukotriene receptor antagonists used in combination with inhaled corticosteroids for the treatment of asthma.
|Autori:||COLUCCI R; FORNAI F; TUCCORI M; ANTONIOLI L; PASQUALETTI G; BLANDIZZI C; DEL TACCA M|
|Titolo:||Tolerability profiles of leukotriene receptor antagonists and long-acting beta2-adrenoceptor agonists in combination with inhaled corticosteroids for treatment of asthma: a review|
|Anno del prodotto:||2007|
|Digital Object Identifier (DOI):||10.1080/02770900701247178|
|Appare nelle tipologie:||1.1 Articolo in rivista|