EnglishAbstract The adenosine A1 receptors of sheep brain membranes have been identified by the specific binding of radiolabeled cyclohexyl[3H]adenosine ([3H]CHA). Pretreatment of membranes with periodate-oxidized CHA causes a dose- and time-dependent decrease in the number of binding sites. No decrease occurs when membranes are pretreated with CHA. Binding of [3H]CHA to the remaining sites occurs with the same characteristics as binding to the untreated receptor population.
| Autori: | |
| Autori: | Martini C; Lucacchini A. |
| Titolo: | AFFINITY LABELING OF ADENOSINE-A1 BINDING-SITES |
| Anno del prodotto: | 1987 |
| Digital Object Identifier (DOI): | 10.1111/j.1471-4159.1987.tb00947.x |
| Appare nelle tipologie: | 1.1 Articolo in rivista |
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