EnglishThree new ligands for odorant-binding proteins (OBPs) have been prepared, to be used in protein structure studies: the photoaffinity label 2-azido-4-butyl-5-propylthiazole, the NMR probe 2-trifluoromethyl-4-butyl-5-propylthiazole and the X-ray probe 2-amino-4-butyl-5-propylselenazole. All three compounds bind the bovine OBP with dissociation constants in the micromolar range.
| Autori: | |
| Autori: | NAPOLITANO E; PELOSI P |
| Titolo: | SYNTHESIS OF THIAZOLE AND SELENAZOLE DERIVATIVES WITH AFFINITY FOR THE ODORANT-BINDING PROTEIN |
| Anno del prodotto: | 1992 |
| Digital Object Identifier (DOI): | 10.1016/S0960-894X(00)80439-4 |
| Appare nelle tipologie: | 1.1 Articolo in rivista |
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