The in vitro activities of human beta-defensin 3 (hBD-3) alone or combined with lysozyme, metronidazole, amoxicillin, and chlorhexidine were investigated with the oral bacteria Streptococcus mutans, Streptococcus sanguinis, Streptococcus sobrinus, Lactobacillus acidophilus, Actinobacillus actinomycetemcomitans, and Porphyromonas gingivalis. hBD-3 showed bactericidal activity against all of the bacterial species tested. The bactericidal effect was enhanced when the peptide was used in combination with the antimicrobial agents mentioned above.
Autori interni: | |
Autori: | MAISETTA G.; BATONI G; ESIN S.; LUPERINI F.; PARDINI M.; BOTTAI D.; FLORIO W.; GIUCA M.R.; GABRIELE M.; CAMPA M. |
Titolo: | Activity of human beta-defensin 3 alone or combined with other antimicrobial agents against oral bacteria |
Anno del prodotto: | 2003 |
Digital Object Identifier (DOI): | 10.1128/AAC.47.10.3349-3351.2003 |
Appare nelle tipologie: | 1.1 Articolo in rivista |
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