Several N-(indol-3-ylglyoxylyl)alanine and glycine ester derivatives were prepared to evaluate the influence of the ester group size both on affinity and on activity at the benzodiazepine receptor. Moreover, indol-3-ylglyoxylic acid esters, closely related to 3-alkoxy-β-carbolines, were synthesized and tested in vitro on the benzodiazepine receptor.
N-(Indol-3-ylglyoxylyl)amino acid ester derivatives. Synthesis and interaction properties at the benzodiazepine receptor
DA SETTIMO PASSETTI, FEDERICO;MARINI, ANNA MARIA;LA MOTTA, CONCETTINA;MARTINI, CLAUDIA;LUCACCHINI, ANTONIO
1995-01-01
Abstract
Several N-(indol-3-ylglyoxylyl)alanine and glycine ester derivatives were prepared to evaluate the influence of the ester group size both on affinity and on activity at the benzodiazepine receptor. Moreover, indol-3-ylglyoxylic acid esters, closely related to 3-alkoxy-β-carbolines, were synthesized and tested in vitro on the benzodiazepine receptor.File in questo prodotto:
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