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EnglishSeveral title compounds were assayed to determine their relative affinity towards the adenosine receptors. Selectivity ratios (SR) showed a prevalent A(I) affinity. The comparison with the selectivity ratios of the corresponding 9-benzyl-8-azaadenines and the comparison between the affinity constant values (K-I) for each receptor of the two series, were performed. The results led us to conclude that A(I) receptors are characterized by more different arrangements which regard especially to 9-benzyl-8-azaadenines.
| Autori interni: | |
| Autori: | Biagi G; Giorgi I; Livi O; Scartoni V; Lucacchini A; Martini C; Tacchi P |
| Titolo: | 2-Aryl-8-Azaadenosines: Structure-Activity Relationships in the Binding with A1 and A2 Receptors. A Comparison with the Corresponding 9-Benzyl-8-Azaadenines |
| Anno del prodotto: | 1994 |
| Appare nelle tipologie: | 1.1 Articolo in rivista |
File in questo prodotto:
http://hdl.handle.net/11568/204843
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