The inosose derivative 3 was obtained with high stereoselectivity by intramolecular aldol condensation of the aldohexos-5-ulose derivative 2, and it was selectively reduced and debenzylated to give epi-inositol in high yield. The stereochemistry and the preferred conformations of compounds 3–7 were determined through 1D and 2D NMR experiments.
|Autori:||PISTARÀ V; BARILI P.L; CATELANI G; CORSARO A; D'ANDREA F; FISICHELLA S|
|Titolo:||A new highly stereoselective synthesis of epi-inositol from D-galactose|
|Anno del prodotto:||2000|
|Digital Object Identifier (DOI):||10.1016/S0040-4039(00)00360-9|
|Appare nelle tipologie:||1.1 Articolo in rivista|