This paper reports the preparation of new triazolepyridazine derivatives bearing in the 1 position an acidic substituent, on the basis of a working hypothesis relating these compounds to 1,2,3-triazole derivatives, effective in vitro inhibitors of the prostaglandin synthesis. The tested compounds were lacking of biological activity.
1,2,3-Trizoles[4,5-d]piridazines. Analogues of Prostaglandin Synthesis Inhibitors
GIORGI, IRENE;LUCACCHINI, ANTONIO
1993-01-01
Abstract
This paper reports the preparation of new triazolepyridazine derivatives bearing in the 1 position an acidic substituent, on the basis of a working hypothesis relating these compounds to 1,2,3-triazole derivatives, effective in vitro inhibitors of the prostaglandin synthesis. The tested compounds were lacking of biological activity.File in questo prodotto:
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