A new insoluble polymer containing a Cinchona alkaloid derivative has been synthesized and used as chiral ligand in the heterogeneous enantioselective dihydroxylation of olefins. It is shown that the enantioselectivity of the optically active diols obtained from both aliphatic and aromatic substrates is always comparable to that observed in the homogeneous phase under the same reaction conditions. A method for evaluating the enantiomeric excesses of the optically active products is also described.
|Autori:||PETRI A; Pini D; Rapaccini S; Salvadori P|
|Titolo:||Synthesis of Optically Active Diols Using an Efficient Polymer Bound Cinchona Alkaloid Derivative|
|Anno del prodotto:||1995|
|Appare nelle tipologie:||1.1 Articolo in rivista|