The NM23-Hl gene is a putative tumor suppressor gene that may be important in the metastasic process. Recent genetic and immunological data indicate that the NM23-Hl gene encodes a protein with nucleoside diphosphate (NDP) kinase activity. The mapping of NM23-Hl by panels of rodent-human somatic cell hybrids and in situ hybridization showed that the gene is located in human chromosome band 17q22. A two-allele polymorphism with BglII was demonstrated.

The NM23 gene maps to human chromosome band 17q22 and shows a restriction fragment length polymorphism with BglII.

BEVILACQUA, GENEROSO
1992

Abstract

The NM23-Hl gene is a putative tumor suppressor gene that may be important in the metastasic process. Recent genetic and immunological data indicate that the NM23-Hl gene encodes a protein with nucleoside diphosphate (NDP) kinase activity. The mapping of NM23-Hl by panels of rodent-human somatic cell hybrids and in situ hybridization showed that the gene is located in human chromosome band 17q22. A two-allele polymorphism with BglII was demonstrated.
Varesco, L; Caligo, Ma; Simi, P; Black, Dm; Nardini, V; Casarino, L; Rocchi, M; Ferrara, G; Solomon, E; Bevilacqua, Generoso
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11568/20665
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