The NM23-Hl gene is a putative tumor suppressor gene that may be important in the metastasic process. Recent genetic and immunological data indicate that the NM23-Hl gene encodes a protein with nucleoside diphosphate (NDP) kinase activity. The mapping of NM23-Hl by panels of rodent-human somatic cell hybrids and in situ hybridization showed that the gene is located in human chromosome band 17q22. A two-allele polymorphism with BglII was demonstrated.
|Autori:||Varesco L; Caligo MA; Simi P; Black DM; Nardini V; Casarino L; Rocchi M; Ferrara G; Solomon E; Bevilacqua G|
|Titolo:||The NM23 gene maps to human chromosome band 17q22 and shows a restriction fragment length polymorphism with BglII.|
|Anno del prodotto:||1992|
|Appare nelle tipologie:||1.1 Articolo in rivista|