The cytosolic (cEH) and the microsomal epoxide hydrolase (mEH) hydrolyse styrene oxide and trans-1-phenylpropene oxide with different enantioselectivity and regioselectivity. While mEH always leads to a regiospecific and enantioselective opening at the non-benzylic oxirane carbon, cEH gives a non-regioselective and non-enantioselective attack to styrene oxide and a regiospecific and non-enantioselective snack at the benzylic carbon of 1-phenylpropene oxide.
Autori interni: | |
Autori: | BELLUCCI G; CHIAPPE C; CORDONI A; MARIONI F |
Titolo: | DIFFERENT ENANTIOSELECTIVITY AND REGIOSELECTIVITY OF THE CYTOSOLIC AND MICROSOMAL EPOXIDE HYDROLASE CATALYZED-HYDROLYSIS OF SIMPLE PHENYL-SUBSTITUTED EPOXIDES |
Anno del prodotto: | 1994 |
Digital Object Identifier (DOI): | 10.1016/S0040-4039(00)73156-X |
Appare nelle tipologie: | 1.1 Articolo in rivista |
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