The reductive cleavage of nitrosobenzene-derived cycloadducts with appropriately protected 1,2-dihydropyridines allows a novel and simple obtainment of substituted N-[1-(1-phenyl-1H-pyrrol-2-yl)alkylamides. This synthesis can also be carried out in a very simple, mild, and practical one-pot procedure without isolation of the corresponding nitrosobenzene cycloadduct by means of catalytic amounts of CuCl.
|Autori:||Francesco Berti;Valeria Di Bussolo;Mauro Pineschi|
|Titolo:||Synthesis of Protected (1-Phenyl-1H-pyrrol-2-yl)-alkane-1-amines from Phenylnitroso Diels?Alder Adducts with 1,2-Dihydropyridines|
|Anno del prodotto:||2013|
|Digital Object Identifier (DOI):||10.1021/jo4009996|
|Appare nelle tipologie:||1.1 Articolo in rivista|