Genotoxic effects in freshwater Triclads after exposure to C riSO)3, chemical used in tanning processing. Freshwater Triclads, common invertebrates in unpolluted aquatic ecosystems, have been utilized as potential genotoxicity biomarkers. Some variations in the pattern of protein synthesis have been evidenced as a genomic response after exposure to toxic chemicals, in particular chromium sulphate, used in tanning processes. At the same time, in different samples, heat shock treatments were performed. Both treatments produced a drastic immediate decrease in the protein synthesis, observed by SDS-PAGE electrophoresis and fluorography. After 12 hours, fluorograms showed gradual restoring of protein synthesis followed by expression of specific polypeptides. As an example, the 41 kDa protein, synthesized in response to chromium sulphate, appeared to be specific and different from the two proteins (46 kDa and 55 kDa) detected after heat-shock treatments.

Effetti genotossici in Tricladi d'acqua dolce in seguito ad esposizione a solfato di cromo, un composto usato nell'attività conciaria

BATISTONI, RENATA;DERI, PAOLO
1998

Abstract

Genotoxic effects in freshwater Triclads after exposure to C riSO)3, chemical used in tanning processing. Freshwater Triclads, common invertebrates in unpolluted aquatic ecosystems, have been utilized as potential genotoxicity biomarkers. Some variations in the pattern of protein synthesis have been evidenced as a genomic response after exposure to toxic chemicals, in particular chromium sulphate, used in tanning processes. At the same time, in different samples, heat shock treatments were performed. Both treatments produced a drastic immediate decrease in the protein synthesis, observed by SDS-PAGE electrophoresis and fluorography. After 12 hours, fluorograms showed gradual restoring of protein synthesis followed by expression of specific polypeptides. As an example, the 41 kDa protein, synthesized in response to chromium sulphate, appeared to be specific and different from the two proteins (46 kDa and 55 kDa) detected after heat-shock treatments.
Batistoni, Renata; Genovese, M.; Deri, Paolo
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Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/11568/229954
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