Synthesis of New 3-Benzyl-5-Phenyl-7-Alkylaminothiazolo[4,5-d]pyrimidine-2(3H)-Thiones.)

Biagi, G; Giorgi, Irene; Livi, O; Scartoni, V.

This paper describes the preparation of title compounds starting from 3-benzyl-4-amino-5-carboxyamidothiazole-2(3H)-thione, which, by heating with alkyl orthobenzoates, was converted into 3-benzyl-5-phenyl-7-alkoxy-thiazolo[4,5-d]pyrimidines. The treatment of these compounds with hydrobromic acid in acetic acid gave 3-benzyl-5-phenyl-7-oxo-thiazolo[4,5-d]pyrimidine-2(3H)-thione which, by reaction with phosphorus oxychloride and subsequent substitution of the halogen with amines, gave the corresponding title compounds.

Autori:	Biagi G GIORGI, IRENE Livi O Scartoni V. mostra contributor esterni nascondi contributor esterni
Autori:	Biagi G; Giorgi I; Livi O; Scartoni V
Titolo:	Synthesis of New 3-Benzyl-5-Phenyl-7-Alkylaminothiazolo[4,5-d]pyrimidine-2(3H)-Thiones.)
Anno del prodotto:	1995
Appare nelle tipologie:	1.1 Articolo in rivista

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Utilizza questo identificativo per citare o creare un link a questo documento:
http://hdl.handle.net/11568/23314

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