A 13-year-old intact male cat was submitted to castration after the finding of the enlargement of the right testis during the clinical visit. Macroscopically, a nodule of 2 cm of diameter was observed on the cut surface of the enlarged testis. Histologically, the nodule was composed by polyhedral to elongated cells with a large, eosinophilic, and vacuolated cytoplasm and small, round, and dark nuclei. These cells were arranged in acinar structures and solid sheets. The tumour was diagnosed as a Leydig cell tumour. Immunohistochemical analysis revealed that neoplastic cells were vimentin, calretinin, and melan-A positive, whereas a lack of immunoreactivity to cytokeratins confirmed the diagnosis. To our knowledge, this is the first description of a feline Leydig cells tumour without any concurrent testicular neoplasm or in a nonretained testis.
|Autori:||Asproni, Pietro; Millanta, Francesca; Lorenzi, Davide; Poli, Alessandro|
|Titolo:||A Leydig cell tumour in a cat: histological and immunohistochemical findings|
|Anno del prodotto:||2013|
|Digital Object Identifier (DOI):||10.1155/2013/670398|
|Appare nelle tipologie:||1.1 Articolo in rivista|
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|Asproni et al_A Leydig cell tumour in a cat_Case report Vet Med 2013 ID 670398.pdf||Versione finale editoriale||Open AccessVisualizza/Apri|