An antibiotic polyketide, Cryptosporioptide (1) was isolated from the culture extract of the endophytic fungus Cryptosporiopsis sp. The structure of Cryptosporioptide has been established with the help of 1D ((1)H, (13)C), 2D NMR (HSQC, HMBC, COSY, NOESY) techniques and mass spectrometry (FABMS, HRFABMS). The absolute configuration was established by means of electronic circular dichroism (ECD). Cryptosporioptide exhibited both lipoxygenase inhibitory and anti-Bacillus megaterium activities.

Cryptosporioptide: A bioactive polyketide produced by an endophytic fungus Cryptosporiopsis sp.

PESCITELLI, GENNARO;
2013

Abstract

An antibiotic polyketide, Cryptosporioptide (1) was isolated from the culture extract of the endophytic fungus Cryptosporiopsis sp. The structure of Cryptosporioptide has been established with the help of 1D ((1)H, (13)C), 2D NMR (HSQC, HMBC, COSY, NOESY) techniques and mass spectrometry (FABMS, HRFABMS). The absolute configuration was established by means of electronic circular dichroism (ECD). Cryptosporioptide exhibited both lipoxygenase inhibitory and anti-Bacillus megaterium activities.
Muhammad, Saleem; Muhammad Imran, Tousif; Naheed, Riaz; Ishtiaq, Ahmed; Barbara, Schulz; Muhammad, Ashraf; Rumana, Nasar; Pescitelli, Gennaro; Hidayat, Hussain; Abdul, Jabbar; Nusrat, Shafiq; Karsten, Krohn
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11568/238412
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