Killed Staphylococcus aureus strain Cowan I cells inhibit contact sensitivity to oxazolone in mice, when given intravenously 24-72 h before sensitization. With transfer experiments it was found that the cells responsible for the suppression are antigen-specific, nylon-adherent, resistant to antitheta serum + C, and sensitive to anti-mouse Ig serum + C. These suppressor B cells bear anti-oxazolone immunoglobulins and appear to exert their suppressive activity by preventing the contact sensitizer from reaching the specific reactive T cells.
Autori interni: | |
Autori: | BENEDETTINI G; DELIBERO G; MORI L; CAMPA M |
Titolo: | STAPHYLOCOCCUS-AUREUS INHIBITS CONTACT SENSITIVITY TO OXAZOLONE BY ACTIVATING SUPPRESSOR B-CELLS IN MICE |
Anno del prodotto: | 1984 |
Appare nelle tipologie: | 1.1 Articolo in rivista |
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