Killed Staphylococcus aureus strain Cowan I cells inhibit contact sensitivity to oxazolone in mice, when given intravenously 24-72 h before sensitization. With transfer experiments it was found that the cells responsible for the suppression are antigen-specific, nylon-adherent, resistant to antitheta serum + C, and sensitive to anti-mouse Ig serum + C. These suppressor B cells bear anti-oxazolone immunoglobulins and appear to exert their suppressive activity by preventing the contact sensitizer from reaching the specific reactive T cells.
|Autori:||BENEDETTINI G; DELIBERO G; MORI L; CAMPA M|
|Titolo:||STAPHYLOCOCCUS-AUREUS INHIBITS CONTACT SENSITIVITY TO OXAZOLONE BY ACTIVATING SUPPRESSOR B-CELLS IN MICE|
|Anno del prodotto:||1984|
|Appare nelle tipologie:||1.1 Articolo in rivista|