To examine the predictive value of early developmental testing for identifying neuromotor and perceptual-motor impairment at school age in children with neonatal encephalopathy (NE).Eighty full term infants with NE were followed longitudinally. Where possible, children were tested on the Griffiths scales at 1 and 2 years and at 5-6 years, on the Touwen Examination, Movement ABC, and WPPSI. The relation between the Griffiths scores and later outcome measures was examined using correlation coefficients and sensitivity and specificity values.By 2 years, 25 children with cerebral palsy were too severely impaired to be formally assessed and remained so at 5-6 years. Abnormal Griffiths scores were obtained by 12\% and 7\% of the children at 1 and 2 years respectively. At 5-6 years, 33\% had poor Movement ABC scores and 15\% poor WPPSI scores. The highest correlation between Griffiths scores and the outcome measures was for the Movement ABC (0.72), although this accounted for only 50\% of the variance. Sensitivity scores for the Movement ABC were below 70\% but specificity was 100\%.A poor score on the Griffiths scales at 1 and/or 2 years is a good predictor of impairment at school age. However, a normal score in the early years cannot preclude later neurological, perceptual-motor, or cognitive abnormalities.
|Autori:||Barnett, A. L.; Guzzetta, A.; Mercuri, E.; Henderson, S. E.; Haataja, L.; Cowan, F.; Dubowitz, L.|
|Titolo:||Can the Griffiths scales predict neuromotor and perceptual-motor impairment in term infants with neonatal encephalopathy?|
|Anno del prodotto:||2004|
|Digital Object Identifier (DOI):||10.1136/adc.2002.019349|
|Appare nelle tipologie:||1.1 Articolo in rivista|