Cardiac health is dependent on the heart’s ability to utilize different substrates to support the overall oxidative metabolism. To characterize a variety of cardiac diseases, there is an ever growing demand for accurate noninvasive approach of myocardial substrate metabolism evaluation. Data obtained from quantitative metabolic imaging modalities add functional information to the anatomic imaging modalities and can aid patient management. The goal of this review is to emphasize the role of noninvasive imaging techniques (such as PET, SPECT, MR spectroscopy and spectroscopic imaging) to detect the metabolic footprints of heart diseases. The advancement on models and methods to estimate kinetic parameters of dynamic processes using data acquired from cardiac imaging modalities are discussed.
Models and methods in cardiac imaging for metabolism studies
LANDINI, LUIGI
2014-01-01
Abstract
Cardiac health is dependent on the heart’s ability to utilize different substrates to support the overall oxidative metabolism. To characterize a variety of cardiac diseases, there is an ever growing demand for accurate noninvasive approach of myocardial substrate metabolism evaluation. Data obtained from quantitative metabolic imaging modalities add functional information to the anatomic imaging modalities and can aid patient management. The goal of this review is to emphasize the role of noninvasive imaging techniques (such as PET, SPECT, MR spectroscopy and spectroscopic imaging) to detect the metabolic footprints of heart diseases. The advancement on models and methods to estimate kinetic parameters of dynamic processes using data acquired from cardiac imaging modalities are discussed.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
