In 8 children with selective IgA deficiency (serum IgA less than 5 mg/dl, secretory IgA less than 0.5 mg/dl in unstimulated saliva) immunofluorescent staining of intestinal biopsy specimens revealed the presence of IgA-containing plasma cells. This finding supports the hypothesis that in the intestinal mucosa of patients with IgA deficiency B lymphocytes undergo "sterile" differentiation into IgA-containing plasma cells probably incapable of secreting the IgA synthesized

IgA-containing plasma cells in the intestinal mucosa of children with selective IgA deficiency.

MAGGIORE, GIUSEPPE;
1982

Abstract

In 8 children with selective IgA deficiency (serum IgA less than 5 mg/dl, secretory IgA less than 0.5 mg/dl in unstimulated saliva) immunofluorescent staining of intestinal biopsy specimens revealed the presence of IgA-containing plasma cells. This finding supports the hypothesis that in the intestinal mucosa of patients with IgA deficiency B lymphocytes undergo "sterile" differentiation into IgA-containing plasma cells probably incapable of secreting the IgA synthesized
Scotta, Ms; Maggiore, Giuseppe; de Giacomo, C; Martini, A; Burgio, Vl; Ugazio, Ag
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11568/6690
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