(R)- And (S)-3-methylheneicosan-2-one [(R)- and (S)-I] were prepd. from (R)- and (S)-Br(CH2)3CHMeCO2H [(R)- and (S)-II], resp, in ∼12 steps. Thus, Me(CH2)12COCH2CO2Me was alkylated by (R)-II and the product was converted to (R)-Me(CH2)12CO(CH2)4CHMeCO2H, which was reduced to (R)-Me(CH2)17CHMeCO2H, which was methylated by MeLi to give (R)-I.
|Autori interni:||ROSSI, RENZO|
|Autori:||ROSSI R.; CARPITA A; Marasco M.|
|Titolo:||Insect pheromones. Synthesis of both enantiomers of 3-methyl-2-heneicosanone, an analog of the sex pheromone of the German cockroach|
|Anno del prodotto:||1981|
|Appare nelle tipologie:||1.1 Articolo in rivista|