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EnglishThere are several guidelines addressing the issues around the use of NSAIDs. However, none has specifically addressed the upper versus lower gastrointestinal (GI) risk of COX-2 selective and non-selective compounds nor the interaction at both the GI and cardiovascular (CV) level of either class of drugs with low-dose aspirin. This Consensus paper aims to develop statements and guidance devoted to these specific issues through a review of current evidence by a multidisciplinary group of experts.
| Autori interni: | ||
| Autori: | Scarpignato, Carmelo; Lanas, Angel; Blandizzi, Corrado; Lems, Willem F; Hermann, Matthias; Hunt, Richard H | |
| Titolo: | Safe prescribing of non-steroidal anti-inflammatory drugs in patients with osteoarthritis--an expert consensus addressing benefits as well as gastrointestinal and cardiovascular risks | |
| Anno del prodotto: | 2015 | |
| Abstract: | There are several guidelines addressing the issues around the use of NSAIDs. However, none has specifically addressed the upper versus lower gastrointestinal (GI) risk of COX-2 selective and non-selective compounds nor the interaction at both the GI and cardiovascular (CV) level of either class of drugs with low-dose aspirin. This Consensus paper aims to develop statements and guidance devoted to these specific issues through a review of current evidence by a multidisciplinary group of experts. | |
| Digital Object Identifier (DOI): | 10.1186/s12916-015-0285-8 | |
| Appare nelle tipologie: | 1.1 Articolo in rivista |
File in questo prodotto:
| File | Descrizione | Tipologia | Licenza | |
|---|---|---|---|---|
| SCARPIGNATO-LANAS-BMC[NON-STEROIDAL-OSTEOART]2015.pdf | ARTICOLO PRINCIPALE | Versione finale editoriale |  | Open AccessVisualizza/Apri |
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