The first section of this chapter is dedicated to the principles of vaccinology, a science which has given a relevant contribution to control several infectious threats such as smallpox, rabies, tetanus, diphtheria, poliomyelitis and more recently hepatitis B and papillomavirus infection. How biotechnology has contributed to improve vaccine strategies by the use of genetic vaccines (DNA-vaccines, recombinant vaccines, etc.) is discussed. Reverse vaccinology and subtractive reverse vaccinology are illustrated. Plant-based vaccines and nanovaccines are also described. Two more sections are dedicated to the routes of vaccine administration and to the most important adjuvants used, respectively.

Vaccines

BRUSCHI, FABRIZIO
2015

Abstract

The first section of this chapter is dedicated to the principles of vaccinology, a science which has given a relevant contribution to control several infectious threats such as smallpox, rabies, tetanus, diphtheria, poliomyelitis and more recently hepatitis B and papillomavirus infection. How biotechnology has contributed to improve vaccine strategies by the use of genetic vaccines (DNA-vaccines, recombinant vaccines, etc.) is discussed. Reverse vaccinology and subtractive reverse vaccinology are illustrated. Plant-based vaccines and nanovaccines are also described. Two more sections are dedicated to the routes of vaccine administration and to the most important adjuvants used, respectively.
Bruschi, Fabrizio
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Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/11568/750393
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