We synthetically present here unpublished results on β2M removal during HD treatments with dialysis membranes having different flux and adsorption capacities to clarify if the spectrophotometric analysis of spent dialysate may allow the possibility to monitor the removal of β2M during HD. These results were obtained from the analyses of serum and spent dialysate samples of the 22 MHD patients (16 men, 6 women). Serum and spent dialysate concentrations of β2M were measured with an immunonephelometric method (Siemens, BNAII) and compared with absorbance and fluorescence values. We conclude that the removal of β2M cannot be evaluated by spectrophotometric analysis of spent dialysate.
The Removal of β2-Microglobulin in Spent Dialysate Cannot Be Monitored by Spectrophotometric Analysis
DONADIO, CARLO;GHIMENTI, SILVIA;ONOR, MASSIMO;COLOMBINI, ELISA;FUOCO, ROGER;DI FRANCESCO, FABIO
2015-01-01
Abstract
We synthetically present here unpublished results on β2M removal during HD treatments with dialysis membranes having different flux and adsorption capacities to clarify if the spectrophotometric analysis of spent dialysate may allow the possibility to monitor the removal of β2M during HD. These results were obtained from the analyses of serum and spent dialysate samples of the 22 MHD patients (16 men, 6 women). Serum and spent dialysate concentrations of β2M were measured with an immunonephelometric method (Siemens, BNAII) and compared with absorbance and fluorescence values. We conclude that the removal of β2M cannot be evaluated by spectrophotometric analysis of spent dialysate.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
