*PCL guides tested in this study seem to be biocompatible: signs of rejection were never detected. The presence of a new-formed bone witness osteo-conductivity of the scaffold. Histological data showed that osteogenesis mainly arise from the periostium of ulna, initially reacting to form a bridge toward the scaffold. Further studies should investigate if modifications in the composition of the scaffold may increase its osteoconductivity and osteoinductivity.
Poly ε-caprolactone scaffold in a rabbit critical size defects model: Histological observations
MIRAGLIOTTA, VINCENZO;BARSOTTI, GIOVANNI;PUPPI, DARIO;COLI, ALESSANDRA;STORNELLI, MARIA RITA;BRIGANTI, ANGELA;GIANNESSI, ELISABETTA;CARLUCCI, FABIO;CHIELLINI, FEDERICA;
2015
Abstract
*PCL guides tested in this study seem to be biocompatible: signs of rejection were never detected. The presence of a new-formed bone witness osteo-conductivity of the scaffold. Histological data showed that osteogenesis mainly arise from the periostium of ulna, initially reacting to form a bridge toward the scaffold. Further studies should investigate if modifications in the composition of the scaffold may increase its osteoconductivity and osteoinductivity.File in questo prodotto:
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