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English*PCL guides tested in this study seem to be biocompatible: signs of rejection were never detected. The presence of a new-formed bone witness osteo-conductivity of the scaffold. Histological data showed that osteogenesis mainly arise from the periostium of ulna, initially reacting to form a bridge toward the scaffold. Further studies should investigate if modifications in the composition of the scaffold may increase its osteoconductivity and osteoinductivity.
| Autori interni: | |
| Autori: | Miragliotta, Vincenzo; Barsotti, Giovanni; Puppi, Dario; Coli, Alessandra; Stornelli, Maria Rita; Briganti, Angela; Giannessi, Elisabetta; Mota, C.; Carlucci, Fabio; Chiellini, Federica; Dini, Francesca |
| Titolo: | Poly ε-caprolactone scaffold in a rabbit critical size defects model: Histological observations |
| Anno del prodotto: | 2015 |
| Abstract: | *PCL guides tested in this study seem to be biocompatible: signs of rejection were never detected. The presence of a new-formed bone witness osteo-conductivity of the scaffold. Histological data showed that osteogenesis mainly arise from the periostium of ulna, initially reacting to form a bridge toward the scaffold. Further studies should investigate if modifications in the composition of the scaffold may increase its osteoconductivity and osteoinductivity. |
| Appare nelle tipologie: | 1.1 Articolo in rivista |
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| 5161-18354-6-PB.pdf | Versione finale editoriale |  | Open AccessVisualizza/Apri |
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