Population aging has imposed cost-effective alternatives to blooddonations. Artificial blood is still at the preliminary stages of development, and the need for viable cells seems unsurmountable. Because large numbers of viable cellsmust be promptly available for clinical use, stem cell technologies, expansion, and banking represent ideal tools to ensure a regular supply. Provided key donors can be identified, induced pluripotent stemcell (iPSC) technology could pave theway to a newera in transfusionmedicine, just as it is alreadydoing inmany other fields of medicine. The present review summarizes the current state of research on iPSC technology in the field of blood banking, highlighting hurdles, and promises.

Effect of induced pluripotent stem cell technology in blood banking

FOCOSI, DANIELE;PISTELLO, MAURO
2016-01-01

Abstract

Population aging has imposed cost-effective alternatives to blooddonations. Artificial blood is still at the preliminary stages of development, and the need for viable cells seems unsurmountable. Because large numbers of viable cellsmust be promptly available for clinical use, stem cell technologies, expansion, and banking represent ideal tools to ensure a regular supply. Provided key donors can be identified, induced pluripotent stemcell (iPSC) technology could pave theway to a newera in transfusionmedicine, just as it is alreadydoing inmany other fields of medicine. The present review summarizes the current state of research on iPSC technology in the field of blood banking, highlighting hurdles, and promises.
2016
Focosi, Daniele; Pistello, Mauro
File in questo prodotto:
File Dimensione Formato  
sctm20150257_rp2.pdf

solo utenti autorizzati

Descrizione: Articolo principale
Tipologia: Versione finale editoriale
Licenza: NON PUBBLICO - Accesso privato/ristretto
Dimensione 961.46 kB
Formato Adobe PDF
961.46 kB Adobe PDF   Visualizza/Apri   Richiedi una copia

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11568/788083
Citazioni
  • ???jsp.display-item.citation.pmc??? 4
  • Scopus 8
  • ???jsp.display-item.citation.isi??? 6
social impact