Reduction of intestinal load of phosphorus is important for the prevention and treatment of chronic kidney disease (CKD)-mineral and bone disorder (MBD). However, this strategy is limited by patients' poor adherence to dietary prescription and by the existence of hidden sources of phosphorus. In addition to food containing phosphate-based additives, it was recently claimed that medications may contribute to increase the load of phosphate (P), mainly present as an excipient. To identify medications containing P as an excipient, we performed a systematic screening of medications which could potentially be prescribed for chronic oral therapies in CKD patients.

The extra-phosphate intestinal load from medications: is it a real concern?

CUPISTI, ADAMASCO;MORICONI, DIEGO;D'ALESSANDRO, CLAUDIA;VERDE, FRANCESCO;MARCHINI, MICHELE;SABA, ALESSANDRO;EGIDI, MARIA FRANCESCA
2016-01-01

Abstract

Reduction of intestinal load of phosphorus is important for the prevention and treatment of chronic kidney disease (CKD)-mineral and bone disorder (MBD). However, this strategy is limited by patients' poor adherence to dietary prescription and by the existence of hidden sources of phosphorus. In addition to food containing phosphate-based additives, it was recently claimed that medications may contribute to increase the load of phosphate (P), mainly present as an excipient. To identify medications containing P as an excipient, we performed a systematic screening of medications which could potentially be prescribed for chronic oral therapies in CKD patients.
2016
Cupisti, Adamasco; Moriconi, Diego; D'Alessandro, Claudia; Verde, Francesco; Marchini, Michele; Saba, Alessandro; Egidi, MARIA FRANCESCA
File in questo prodotto:
File Dimensione Formato  
2016_Fosforo_J.Nephrology.pdf

solo utenti autorizzati

Tipologia: Versione finale editoriale
Licenza: NON PUBBLICO - Accesso privato/ristretto
Dimensione 570.39 kB
Formato Adobe PDF
570.39 kB Adobe PDF   Visualizza/Apri   Richiedi una copia

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11568/792674
Citazioni
  • ???jsp.display-item.citation.pmc??? 2
  • Scopus 8
  • ???jsp.display-item.citation.isi??? 7
social impact