CINECA IRIS Institutional Research Information System
IRIS è la soluzione IT che facilita la raccolta e la gestione dei dati relativi alle attività e ai prodotti della ricerca. Fornisce a ricercatori, amministratori e valutatori gli strumenti per monitorare i risultati della ricerca, aumentarne la visibilità e allocare in modo efficace le risorse disponibili.
EnglishGlutamate system is modified by ethanol and contributes both to the euphoric and the dysphoric consequences of intoxication, but there is now growing evidence that the glutamatergic system also plays a central role in the neurobiology and treatment of mood disorders, including major depressive disorders and bipolar disorders.We speculate that, using acamprosate, patients with bipolar depression (BIP-A) can take advantage of the anti-glutamate effect of acamprosate to “survive” in treatment longer than peers suffering from non-bipolar depression (NBIP-A) after detoxification.
| Autori interni: | ||
| Autori: | Maremmani, Angelo Giovanni Icro; Bacciardi, Silvia; Rovai, Luca; Rugani, Fabio; Massimetti, Enrico; Gazzarrini, Denise; Dell'Osso, Liliana; Maremmani, Icro | |
| Titolo: | Six-month outcome in bipolar spectrum alcoholics treated with acamprosate after detoxification: a retrospective study | |
| Anno del prodotto: | 2014 | |
| Abstract: | Glutamate system is modified by ethanol and contributes both to the euphoric and the dysphoric consequences of intoxication, but there is now growing evidence that the glutamatergic system also plays a central role in the neurobiology and treatment of mood disorders, including major depressive disorders and bipolar disorders.We speculate that, using acamprosate, patients with bipolar depression (BIP-A) can take advantage of the anti-glutamate effect of acamprosate to “survive” in treatment longer than peers suffering from non-bipolar depression (NBIP-A) after detoxification. | |
| Digital Object Identifier (DOI): | 10.3390/ijerph111212983 | |
| Appare nelle tipologie: | 1.1 Articolo in rivista |
File in questo prodotto:
| File | Descrizione | Tipologia | Licenza | |
|---|---|---|---|---|
| DellOsso_800469.pdf | Versione finale editoriale |  | Open AccessVisualizza/Apri |
Copyright © 2022