Electrophysiological examinations brings some advantages for the assessment of patients with DoC due to their objectivity and high temporal resolution. The P300 component of the ERPs is a positive wave generated when patients detect a rare and unexpected stimulus in a regular train of standard stimuli (i.e. oddball paradigm) and might reflect either the recognition of the target’s intrinsic meaning or the detection of its acoustic salience. In the present work the P300 was acquired in 12 subjects with DoC. The P300 wave could be considered as a prognostic marker to be used in evaluating non-responders DoC patients, in order to “estimate” cognitive residual functions and manage early therapeutic and rehabilitating interventions.
Is there a relation between P300 and behavioural scales in the assessment of patients with Disorders of Consciousness?
Bonfiglio, L.;ROSSI, BRUNO;CARBONCINI, MARIA CHIARA
2016-01-01
Abstract
Electrophysiological examinations brings some advantages for the assessment of patients with DoC due to their objectivity and high temporal resolution. The P300 component of the ERPs is a positive wave generated when patients detect a rare and unexpected stimulus in a regular train of standard stimuli (i.e. oddball paradigm) and might reflect either the recognition of the target’s intrinsic meaning or the detection of its acoustic salience. In the present work the P300 was acquired in 12 subjects with DoC. The P300 wave could be considered as a prognostic marker to be used in evaluating non-responders DoC patients, in order to “estimate” cognitive residual functions and manage early therapeutic and rehabilitating interventions.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
