A parallel manipulator with three translational degrees of freedom for microfabrication of biomaterials was designed for a given workspace. The device was opportunely designed to mount the following biofabrication tools on its mobile platform: a pressure-driven extrusion tool, a piston-driven extrusion tool, and an electrospinning tool. Taking advantage of the modularity of the system, it was possible to combine these different techniques to obtain multimaterial and multiscale scaffolds with structural and mechanical characteristics more similar to biological tissues. In this work, hydrogel-based composite scaffolds were fabricated as a demonstration.
Machine design for multimaterial processing
DE MARIA, CARMELO;DE ACUTIS, AURORA;VOZZI, GIOVANNI
2016-01-01
Abstract
A parallel manipulator with three translational degrees of freedom for microfabrication of biomaterials was designed for a given workspace. The device was opportunely designed to mount the following biofabrication tools on its mobile platform: a pressure-driven extrusion tool, a piston-driven extrusion tool, and an electrospinning tool. Taking advantage of the modularity of the system, it was possible to combine these different techniques to obtain multimaterial and multiscale scaffolds with structural and mechanical characteristics more similar to biological tissues. In this work, hydrogel-based composite scaffolds were fabricated as a demonstration.| File | Dimensione | Formato | |
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