Three new sesquiterpenes, 1β,4β,1α,10α-diepoxy-6-oxo-7α,8α-diacetoxygermacr-11-en-12-oic acid methyl ester named as spiraloside (1), 1α,10α-epoxy-8α,13-diacetylpiptocarphol (2), and 5β-(2-methylacryloyloxy)spicatocadinanolide A (3) along with two known compounds were isolated from Pseudelephantopus spiralis aerial part extracts. Their structures were determined by spectroscopic and spectrometric techniques including 1D- and 2D NMR, and MS analyses. Compounds 1-3 were assayed against PC-3 and MCF-7 cancer cell lines, showing no activity.
Phytochemical investigation of Pseudelephantopus spiralis (Less.) Cronquist
BRACA, ALESSANDRA
;
2016-01-01
Abstract
Three new sesquiterpenes, 1β,4β,1α,10α-diepoxy-6-oxo-7α,8α-diacetoxygermacr-11-en-12-oic acid methyl ester named as spiraloside (1), 1α,10α-epoxy-8α,13-diacetylpiptocarphol (2), and 5β-(2-methylacryloyloxy)spicatocadinanolide A (3) along with two known compounds were isolated from Pseudelephantopus spiralis aerial part extracts. Their structures were determined by spectroscopic and spectrometric techniques including 1D- and 2D NMR, and MS analyses. Compounds 1-3 were assayed against PC-3 and MCF-7 cancer cell lines, showing no activity.File in questo prodotto:
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