PURPOSE: To assess whether contrast-enhanced T1-weighted MR Cholangiography may provide additional information in the evaluation of biliary complications in orthotopic liver transplant recipients. MATERIAL AND METHODS: Eighty liver transplant patients with suspicion of biliary adverse events underwent MR imaging at 1.5 T scanner. After acquisition of axial T1-/T2-weighted images and conventional T2-weighted MR Cholangiography (image set 1), 3D gradient-echo T1-weighted fat-suppressed LAVA (Liver Acquisition with Volume Acceleration) sequences were obtained about 30 min after intravenous infusion of mangafodipir trisodium (Mn-DPDP,Teslascan(®)) (image set 2). The diagnostic value of mangafodipir trisodium-enhanced MR Cholangiography in the detection of biliary complications was tested by separate analysis results of image set 1 alone and image set 1 and 2 together. MRI results were correlated with direct cholangiography in 46 patients, surgery in 14 and/or clinical-radiological follow-up in the remaining 20 cases. RESULTS: The level of confidence in the assessment of biliary adverse events was significantly increased by the administration of mangafodipir trisodium (p < 0.05). Particularly, contrast-enhanced T1-weighted LAVA sequences tended to out-perform conventional T2-weighted MR Cholangiography in the delineation of anastomotic and non-anastomotic biliary strictures and in the diagnosis of biliary leak. CONCLUSIONS: Contrast-enhanced T1-weighted MR Cholangiography may improve the level of diagnostic confidence provided by conventional T2-weighted MR Cholangiography in the evaluation of biliary complications after orthotopic liver transplantation.
Biliary complications following orthotopic liver transplantation: May contrast-enhanced MR Cholangiography provide additional information? / Boraschi, P; Donati, F; Gigoni, R; Filipponi, F.. - In: EUROPEAN JOURNAL OF RADIOLOGY. - ISSN 0720-048X. - ELETTRONICO. - 3(2016), pp. 108-116.
|Autori:||Boraschi, P; Donati, F; Gigoni, R; Filipponi, F.|
|Titolo:||Biliary complications following orthotopic liver transplantation: May contrast-enhanced MR Cholangiography provide additional information?|
|Anno del prodotto:||2016|
|Digital Object Identifier (DOI):||10.1016|
|Appare nelle tipologie:||1.1 Articolo in rivista|