Cardiovascular epidemiology has recently highlighted a clear link between serum γ-glutamyltransferase (GGT) and risk for stroke, infarction and cardiovascular death, associated with the evolution of atherosclerosis-related conditions, such as coronary artery and cerebrovascular disease. Thus, serum GGT is now recognized as a cardiovascular prognostic marker. However, the reasons for the association between serum GGT elevations and unfavorable prognosis remain to be defined. Histochemistry and biochemistry have provided intriguing clues, focusing new research approaches on the complex issue of monitoring and treatment of chronic cardiovascular conditions. © 2007 Future Medicine Ltd.
γ-glutamyltransferase and pathogenesis of cardiovascular diseases
EMDIN, MICHELE;FRANZINI, MARIA;PAOLICCHI, ALDO;POMPELLA, ALFONSO
2007-01-01
Abstract
Cardiovascular epidemiology has recently highlighted a clear link between serum γ-glutamyltransferase (GGT) and risk for stroke, infarction and cardiovascular death, associated with the evolution of atherosclerosis-related conditions, such as coronary artery and cerebrovascular disease. Thus, serum GGT is now recognized as a cardiovascular prognostic marker. However, the reasons for the association between serum GGT elevations and unfavorable prognosis remain to be defined. Histochemistry and biochemistry have provided intriguing clues, focusing new research approaches on the complex issue of monitoring and treatment of chronic cardiovascular conditions. © 2007 Future Medicine Ltd.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
