Networks of cytokines have been implicated in both forms of inflammatory bowel disease (IBD): Crohn's disease (CD) and ulcerative colitis (UC). While CD has associated with T-helper type 1 (Th1) immune responses, UC shows Th2 patterns. Recent studies reported that the inflamed intestinal regions in both CD and UC are significantly infiltrated with a newly described set of T helper, the Th17 cells. These cells have unique cytokine responses. These findings prompted us to further explore the cytokine profiles of CD and UC with a special focus on the Th2 and Th17 related mediators.

Crohn's Disease and Ulcerative Colitis Show Unique Cytokine Profiles

ANTONIOLI, LUCA;
2017-01-01

Abstract

Networks of cytokines have been implicated in both forms of inflammatory bowel disease (IBD): Crohn's disease (CD) and ulcerative colitis (UC). While CD has associated with T-helper type 1 (Th1) immune responses, UC shows Th2 patterns. Recent studies reported that the inflamed intestinal regions in both CD and UC are significantly infiltrated with a newly described set of T helper, the Th17 cells. These cells have unique cytokine responses. These findings prompted us to further explore the cytokine profiles of CD and UC with a special focus on the Th2 and Th17 related mediators.
2017
Nemeth, Zoltan H; Bogdanovski, Dorian A; Barratt Stopper, Patricia; Paglinco, Samantha R; Antonioli, Luca; Rolandelli, Rolando H.
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11568/869034
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