The aim of the present paper was to evaluate the antifungal effectiveness of a commercially available enilconazole in fumigant form. The antifungal effectiveness of the disinfectant was evaluated against 140 spores (in clinical animals hair samples) and 72 mycelia samples of M. canis from infected pets. One hundred-thirty-one hair specimens Out of 140 (93.6%) and 66 out of 72 (91.7%) subcultures from mycelia were inactivated after treatment. The statistical analysis did not reveal significant differences between spore and mycelia sensitivity. Sensitivity of both arthrospores and mycelia versus enilconazole was evaluated in order to identify possible differences in the resistance of the dermatophyte in its different forms. At the best of our knowledge such a comparison has not been reported. Infected animals can be massive airborne reservoir of viable fungal particles. Enilconazole in the fumigant form is effective also when mixed with several disinfectants including quaternary ammonium compounds, formaldehyde or hydrogen peroxide, even though Such combinations can cause allergies. The use of this product together with other disinfectants could be useful in the management of infected households.

Susceptibility of Microsporum canis isolated from domestic animals against a commercially available enilconazole in fumigant form

MANCIANTI, FRANCESCA;NARDONI, SIMONA
2004-01-01

Abstract

The aim of the present paper was to evaluate the antifungal effectiveness of a commercially available enilconazole in fumigant form. The antifungal effectiveness of the disinfectant was evaluated against 140 spores (in clinical animals hair samples) and 72 mycelia samples of M. canis from infected pets. One hundred-thirty-one hair specimens Out of 140 (93.6%) and 66 out of 72 (91.7%) subcultures from mycelia were inactivated after treatment. The statistical analysis did not reveal significant differences between spore and mycelia sensitivity. Sensitivity of both arthrospores and mycelia versus enilconazole was evaluated in order to identify possible differences in the resistance of the dermatophyte in its different forms. At the best of our knowledge such a comparison has not been reported. Infected animals can be massive airborne reservoir of viable fungal particles. Enilconazole in the fumigant form is effective also when mixed with several disinfectants including quaternary ammonium compounds, formaldehyde or hydrogen peroxide, even though Such combinations can cause allergies. The use of this product together with other disinfectants could be useful in the management of infected households.
2004
Mancianti, Francesca; Nardoni, Simona
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11568/87174
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